Disease: Rett Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
UBE3A Q05086 ubiquitin protein ligase E3A 1.00 0.561 0.692
MED18 Q9BUE0 mediator complex subunit 18 1.6E-04 0.736 0.423
MBD5 Q9P267 methyl-CpG binding domain protein 5 1.00 0.581 0.808
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
SYN1 P17600 synapsin I Cellular structure 0.99 0.597 0.462
ADARB1 P78563 adenosine deaminase RNA specific B1 Enzyme 0.80 0.588 0.654
ARSD P51689 arylsulfatase D Enzyme 1.6E-03 0.535 0.808
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
GABRD O14764 gamma-aminobutyric acid type A receptor subunit delta Ion channel 0.99 0.558 0.692
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
EIF4E P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 0.94 0.448 0.846
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846