Disease: Pervasive Development Disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
FMR1-AS1 FMR1 antisense RNA 1 0.839 0.231
ARHGEF9 O43307 Cdc42 guanine nucleotide exchange factor 9 Enzyme modulator 1.00 0.691 0.385
SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains 1 1.00 0.678 0.385
SYN1 P17600 synapsin I Cellular structure 0.99 0.597 0.462
AFF2 P51816 AF4/FMR2 family member 2 Transcription factor 1.00 0.636 0.538
NUFIP2 Q7Z417 nuclear FMR1 interacting protein 2 1.00 0.641 0.577
NCS1 P62166 neuronal calcium sensor 1 0.66 0.656 0.615
HTT P42858 huntingtin 1.00 0.548 0.654
PVALB P20472 parvalbumin Calcium-binding protein 8.7E-02 0.547 0.692
UBE3A Q05086 ubiquitin protein ligase E3A 1.00 0.561 0.692
NRXN1 P58400 Q9ULB1 neurexin 1 1.00 0.581 0.692
RSS Russell Silver syndrome 0.578 0.692
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
ARSD P51689 arylsulfatase D Enzyme 1.6E-03 0.535 0.808
GRIN2A Q12879 glutamate ionotropic receptor NMDA type subunit 2A Ion channel 1.00 0.522 0.808
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
MBD5 Q9P267 methyl-CpG binding domain protein 5 1.00 0.581 0.808
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
AVP P01185 arginine vasopressin Signaling 7.4E-02 0.437 0.846
EIF4E P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 0.94 0.448 0.846
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846