Disease: Acromegaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GHRH P01286 growth hormone releasing hormone Signaling 0.15 0.503 0.769
GHRHR Q02643 growth hormone releasing hormone receptor G-protein coupled receptor 1.0E-07 0.568 0.692
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
H3P10 H3 histone pseudogene 10 0.350 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808
IGSF1 Q8N6C5 immunoglobulin superfamily member 1 Receptor 1.00 0.608 0.500
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
LEP P41159 leptin 0.46 0.349 0.846
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MIR21 microRNA 21 0.363 0.846
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NAMPT P43490 nicotinamide phosphoribosyltransferase Signaling 0.98 0.502 0.808