Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731
AURKB Q96GD4 aurora kinase B Kinase 4.5E-03 0.510 0.769
BIRC5 O15392 baculoviral IAP repeat containing 5 Enzyme modulator 5.6E-02 0.495 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FBXW7 Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 1.00 0.465 0.808
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FSCN1 Q16658 fascin actin-bundling protein 1 Cellular structure 0.87 0.504 0.731
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
NES P48681 nestin 1.6E-06 0.450 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
POLE Q07864 DNA polymerase epsilon, catalytic subunit 8.0E-27 0.526 0.731
PPP1R2C O14990 PPP1R2C family member C Enzyme modulator 0.478 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923