Disease: Marfan Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
KLF4 O43474 Kruppel like factor 4 Nucleic acid binding 1.00 0.449 0.769
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923