Disease: Geographic Atrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACAD10 Q6JQN1 acyl-CoA dehydrogenase family member 10 Enzyme 1.0E-30 0.760 0.308
AMD1 P17707 adenosylmethionine decarboxylase 1 Enzyme 0.98 0.593 0.577
AMD1P2 adenosylmethionine decarboxylase 1 pseudogene 2 0.608 0.538
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ARMS2 P0C7Q2 age-related maculopathy susceptibility 2 5.2E-04 0.670 0.308
C1QTNF5 Q9BXJ0 C1q and TNF related 5 0.84 0.663 0.346
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885
CD59 P13987 CD59 molecule (CD59 blood group) 0.61 0.469 0.808
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CFB P00751 complement factor B 4.7E-16 0.532 0.769
CFH P08603 complement factor H 0.86 0.441 0.885
CFI P05156 complement factor I 3.5E-08 0.569 0.731
COL8A1 P27658 collagen type VIII alpha 1 chain Extracellular structure 0.41 0.678 0.538
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
EFEMP1 Q12805 EGF containing fibulin extracellular matrix protein 1 Extracellular structure 1.00 0.540 0.769
HMCN1 Q96RW7 hemicentin 1 3.6E-38 0.736 0.577
HTRA1 Q92743 HtrA serine peptidase 1 Enzyme 4.9E-04 0.532 0.692
IL6 P05231 interleukin 6 0.32 0.248 0.962
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
PGF P49763 placental growth factor Signaling 0.13 0.460 0.846
PLXNA2 O75051 plexin A2 1.1E-06 0.447 0.808