Disease: Hypothyroidism
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALB P02768 albumin Transporter 0.64 0.317 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
COX3 P00414 cytochrome c oxidase III Enzyme 0.546 0.808
DIO2 Q92813 iodothyronine deiodinase 2 0.62 0.590 0.731
DNAH1 Q9P2D7 dynein axonemal heavy chain 1 Enzyme 1.5E-26 0.656 0.615
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
DUOX2 Q9NRD8 dual oxidase 2 Enzyme 4.5E-56 0.533 0.769
DUOXA2 Q1HG44 dual oxidase maturation factor 2 1.3E-15 0.700 0.423
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FOXE1 O00358 forkhead box E1 Transcription factor 0.79 0.573 0.731
FOXI1 Q12951 forkhead box I1 Transcription factor 0.77 0.686 0.462
GLIS3 Q8NEA6 GLIS family zinc finger 3 5.6E-08 0.590 0.654
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
GSN P06396 gelsolin Cellular structure 3.9E-11 0.475 0.885
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
HT Hashimoto thyroiditis 0.505 0.731
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL2 P60568 interleukin 2 0.48 0.336 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
IYD Q6PHW0 iodotyrosine deiodinase 4.1E-03 0.700 0.500
KCNJ10 P78508 potassium inwardly rectifying channel subfamily J member 10 Ion channel 0.15 0.599 0.654