Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846