Disease: Cortical cataract
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ASPG Q86U10 asparaginase 6.2E-13 0.559 0.654
ATF3 P18847 activating transcription factor 3 Transcription factor 8.9E-02 0.494 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846
CCL11 P51671 C-C motif chemokine ligand 11 Signaling 1.0E-02 0.473 0.885
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CCNH P51946 cyclin H Enzyme modulator 8.1E-04 0.595 0.769
CDK7 P50613 cyclin dependent kinase 7 Kinase 4.5E-07 0.566 0.731
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885
CYP11A1 P05108 cytochrome P450 family 11 subfamily A member 1 5.5E-07 0.547 0.731
CYREN Q9BWK5 cell cycle regulator of NHEJ 0.26 0.821 0.269
DDR1 Q08345 discoidin domain receptor tyrosine kinase 1 Kinase 4.6E-06 0.497 0.808
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808
GHSR Q92847 growth hormone secretagogue receptor G-protein coupled receptor 6.6E-03 0.528 0.769
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
GTF2H2 Q13888 general transcription factor IIH subunit 2 Transcription factor 1.6E-02 0.650 0.577
GTF2H3 Q13889 general transcription factor IIH subunit 3 Nucleic acid binding 3.0E-08 0.656 0.615
GTF2H4 Q92759 general transcription factor IIH subunit 4 Transcription factor 4.2E-07 0.573 0.846