Disease: Pulmonary Hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
HAS1 Q92839 hyaluronan synthase 1 1.3E-12 0.670 0.577
HAS2 Q92819 hyaluronan synthase 2 0.99 0.588 0.692
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
HTR2B P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 2.7E-10 0.647 0.538
IL6 P05231 interleukin 6 0.32 0.248 0.962
LOX P28300 lysyl oxidase 0.99 0.447 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808
PRKG1 Q13976 protein kinase cGMP-dependent 1 Kinase 1.00 0.603 0.769