Disease: Idiopathic pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ANXA5 P08758 annexin A5 3.8E-15 0.458 0.769
APLN Q9ULZ1 apelin 0.46 0.497 0.769
ATG5 Q9H1Y0 autophagy related 5 Transporter 0.98 0.462 0.885
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
CHST3 Q7LGC8 carbohydrate sulfotransferase 3 7.2E-03 0.517 0.846
CPT1A P50416 carnitine palmitoyltransferase 1A Enzyme 5.1E-09 0.555 0.808
CPT2 P23786 carnitine palmitoyltransferase 2 Enzyme 4.6E-10 0.542 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846
HAS2 Q92819 hyaluronan synthase 2 0.99 0.588 0.692