Disease: Gastrointestinal Stromal Tumors
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846
PDPN Q86YL7 podoplanin 3.2E-04 0.470 0.769
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MIR139 microRNA 139 0.527 0.808
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MEN1 O00255 menin 1 1.00 0.444 0.808
MAX P61244 MYC associated factor X Transcription factor 0.83 0.553 0.769
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
KRIT1 O00522 KRIT1 ankyrin repeat containing 6.9E-04 0.500 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IFNG P01579 interferon gamma 0.47 0.288 0.962
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923