Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
TFAP2A P05549 transcription factor AP-2 alpha Transcription factor 0.99 0.488 0.769
NSD2 O96028 nuclear receptor binding SET domain protein 2 Epigenetic regulator 1.00 0.507 0.769
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
LETM1 O95202 leucine zipper and EF-hand containing transmembrane protein 1 Transporter 1.2E-06 0.545 0.692
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808
FGF8 P55075 fibroblast growth factor 8 Signaling 0.68 0.507 0.769
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
TCIRG1 Q13488 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 Transporter 2.4E-13 0.565 0.692
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808