Disease: Intervertebral Disc Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846
ADAMTS3 O15072 ADAM metallopeptidase with thrombospondin type 1 motif 3 Enzyme 1.0E-10 0.581 0.808
ADAMTS4 O75173 ADAM metallopeptidase with thrombospondin type 1 motif 4 Enzyme 2.0E-06 0.582 0.692
ADGRG6 Q86SQ4 adhesion G protein-coupled receptor G6 G-protein coupled receptor 6.6E-05 0.666 0.385
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AMH P03971 anti-Mullerian hormone 3.4E-12 0.476 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
DCT P40126 dopachrome tautomerase Enzyme 7.4E-14 0.619 0.654
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
GPC6 Q9Y625 glypican 6 0.14 0.626 0.654
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
IVD P26440 isovaleryl-CoA dehydrogenase Enzyme 1.5E-14 0.705 0.462
LMNA P02545 lamin A/C 1.00 0.384 0.885
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
NFAT5 O94916 nuclear factor of activated T cells 5 Transcription factor 1.00 0.601 0.692