Disease: Hypercholesterolemia, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR6886 microRNA 6886 0.861 0.077
ADPRH P54922 ADP-ribosylarginine hydrolase Enzyme 3.0E-06 0.805 0.231
STAP1 Q9ULZ2 signal transducing adaptor family member 1 Receptor 1.7E-05 0.792 0.231
COG2 Q14746 component of oligomeric golgi complex 2 9.4E-06 0.729 0.423
HDL3 Huntington-like neurodegenerative disorder 2 0.663 0.423
INSIG2 Q9Y5U4 insulin induced gene 2 6.0E-02 0.653 0.500
LDLRAP1 Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 6.5E-06 0.641 0.538
ABCG8 Q9H221 ATP binding cassette subfamily G member 8 Transporter 2.4E-20 0.573 0.538
APOA4 P06727 apolipoprotein A4 5.5E-06 0.582 0.577
APOC2 P02655 apolipoprotein C2 0.40 0.606 0.577
SREBF2 Q12772 sterol regulatory element binding transcription factor 2 0.21 0.566 0.577
ANGPTL3 Q9Y5C1 angiopoietin like 3 Signaling 1.6E-13 0.584 0.577
ABCG5 Q9H222 ATP binding cassette subfamily G member 5 Transporter 3.1E-21 0.592 0.577
CYP7A1 P22680 cytochrome P450 family 7 subfamily A member 1 Enzyme 2.5E-04 0.576 0.615
LIPG Q9Y5X9 lipase G, endothelial type Enzyme 1.0E-10 0.633 0.615
EPHX2 P34913 epoxide hydrolase 2 Enzyme 1.8E-21 0.568 0.654
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LIPA P38571 lipase A, lysosomal acid type Enzyme 5.5E-07 0.564 0.654
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
VLDLR P98155 very low density lipoprotein receptor 2.0E-11 0.558 0.692
MYLIP Q8WY64 myosin regulatory light chain interacting protein 0.18 0.582 0.692
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
SLCO1B1 Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 1.1E-21 0.538 0.731