Disease: Portal Hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACVRL1 P37023 activin A receptor like type 1 Kinase 9.7E-04 0.493 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
ANGPT1 Q15389 angiopoietin 1 Signaling 0.95 0.446 0.808
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
BDKRB2 P30411 bradykinin receptor B2 G-protein coupled receptor 0.12 0.585 0.808
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
GDF2 Q9UK05 growth differentiation factor 2 Signaling 2.5E-03 0.529 0.731
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PDE5A O76074 phosphodiesterase 5A 1.1E-04 0.513 0.731
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923