Disease: Left-Sided Heart Failure
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
EPHX2 P34913 epoxide hydrolase 2 Enzyme 1.8E-21 0.568 0.654
FBLN5 Q9UBX5 fibulin 5 Calcium-binding protein 1.00 0.546 0.692
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
HTR2B P41595 5-hydroxytryptamine receptor 2B G-protein coupled receptor 2.7E-10 0.647 0.538
IL6 P05231 interleukin 6 0.32 0.248 0.962
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885