Disease: Proliferative diabetic retinopathy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
LOX P28300 lysyl oxidase 0.99 0.447 0.846
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885
PLA2G7 Q13093 phospholipase A2 group VII Enzyme 5.3E-22 0.537 0.769
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
SELP P16109 selectin P 5.0E-32 0.460 0.769
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885