Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
BMPR2 | Q13873 | bone morphogenetic protein receptor type 2 | Kinase | 1.00 | 0.538 | 0.654 |
CA9 | Q16790 | carbonic anhydrase 9 | 1.3E-09 | 0.483 | 0.731 | |
CCL2 | P13500 | C-C motif chemokine ligand 2 | Signaling | 0.61 | 0.321 | 0.962 |
CDKN1A | P38936 | cyclin dependent kinase inhibitor 1A | 1.9E-03 | 0.403 | 0.769 | |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
CYBB | P04839 | cytochrome b-245 beta chain | Ion channel | 1.00 | 0.452 | 0.885 |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
EDNRB | P24530 | endothelin receptor type B | G-protein coupled receptor | 9.2E-03 | 0.470 | 0.846 |
EPAS1 | Q99814 | endothelial PAS domain protein 1 | Transcription factor | 0.60 | 0.454 | 0.731 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
GDF2 | Q9UK05 | growth differentiation factor 2 | Signaling | 2.5E-03 | 0.529 | 0.731 |
HDAC1 | Q13547 | histone deacetylase 1 | Epigenetic regulator | 0.61 | 0.460 | 0.846 |
HDAC5 | Q9UQL6 | histone deacetylase 5 | Epigenetic regulator | 1.00 | 0.552 | 0.769 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
HMOX1 | P09601 | heme oxygenase 1 | 9.7E-03 | 0.381 | 0.923 | |
IL13 | P35225 | interleukin 13 | 1.4E-02 | 0.386 | 0.846 | |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
KCNK3 | O14649 | potassium two pore domain channel subfamily K member 3 | Ion channel | 0.90 | 0.584 | 0.654 |
LEPR | P48357 | leptin receptor | Signaling | 0.99 | 0.433 | 0.808 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
NFATC2 | Q13469 | nuclear factor of activated T cells 2 | Transcription factor | 1.00 | 0.525 | 0.731 |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 |