Disease: Thyroid associated opthalmopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
RNH1 P13489 ribonuclease/angiogenin inhibitor 1 Transcription factor 2.6E-10 0.569 0.731
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846
GDF1 P27539 growth differentiation factor 1 Signaling 0.41 0.529 0.692
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
IL12B P29460 interleukin 12B Signaling 1.1E-04 0.480 0.885
SST P61278 somatostatin Signaling 0.34 0.399 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
NAMPT P43490 nicotinamide phosphoribosyltransferase Signaling 0.98 0.502 0.808
SHC3 Q92529 SHC adaptor protein 3 Signaling 4.6E-02 0.587 0.731
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PRKAA1 Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 0.14 0.453 0.846
PRKAA2 P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 3.5E-08 0.456 0.846
PRKAB1 Q9Y478 protein kinase AMP-activated non-catalytic subunit beta 1 Kinase 5.3E-03 0.460 0.846
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
TSHR P16473 thyroid stimulating hormone receptor G-protein coupled receptor 3.0E-15 0.486 0.808
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885