Disease: Dystrophia unguium
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATP6V1B2 P21281 ATPase H+ transporting V1 subunit B2 Transporter 0.99 0.606 0.577
COL17A1 Q9UMD9 collagen type XVII alpha 1 chain 2.3E-27 0.545 0.769
CTC1 Q2NKJ3 CST telomere replication complex component 1 1.6E-11 0.601 0.538
DKC1 O60832 dyskerin pseudouridine synthase 1 Nucleic acid binding 1.00 0.547 0.769
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
EVC P57679 EvC ciliary complex subunit 1 3.5E-25 0.587 0.577
EVC2 Q86UK5 EvC ciliary complex subunit 2 1.0E-34 0.585 0.692
FLNA P21333 filamin A 1.00 0.419 0.846
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
GRHL2 Q6ISB3 grainyhead like transcription factor 2 Transcription factor 1.00 0.590 0.731
IKBKG Q9Y6K9 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Kinase 8.5E-02 0.493 0.769
ITGB4 P16144 integrin subunit beta 4 Receptor 9.5E-19 0.525 0.731
KDF1 Q8NAX2 keratinocyte differentiation factor 1 0.15 0.729 0.269
KRT17 Q04695 keratin 17 1.1E-11 0.531 0.654
LAMA3 Q16787 laminin subunit alpha 3 Enzyme modulator 8.8E-46 0.576 0.731
LAMB3 Q13751 laminin subunit beta 3 Enzyme modulator 2.3E-15 0.558 0.692
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
NHP2 Q9NX24 NHP2 ribonucleoprotein Nucleic acid binding 5.0E-02 0.623 0.654
NOP10 Q9NPE3 NOP10 ribonucleoprotein Nucleic acid binding 0.77 0.631 0.654
PARN O95453 poly(A)-specific ribonuclease Nucleic acid binding 3.7E-04 0.575 0.769
PORCN Q9H237 porcupine O-acyltransferase Enzyme 1.00 0.545 0.692
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
TERC telomerase RNA component 0.471 0.846
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846