Disease: Isolated somatotropin deficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ARNT2 Q9HBZ2 aryl hydrocarbon receptor nuclear translocator 2 Transcription factor 0.99 0.599 0.731
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
EIF2S3 P41091 eukaryotic translation initiation factor 2 subunit gamma Enzyme 0.96 0.604 0.731
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
GHRH P01286 growth hormone releasing hormone Signaling 0.15 0.503 0.769
GHRHR Q02643 growth hormone releasing hormone receptor G-protein coupled receptor 1.0E-07 0.568 0.692
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
GNRH1 P01148 gonadotropin releasing hormone 1 0.15 0.524 0.731
HESX1 Q9UBX0 HESX homeobox 1 8.0E-04 0.561 0.654
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGSF1 Q8N6C5 immunoglobulin superfamily member 1 Receptor 1.00 0.608 0.500
LHX3 Q9UBR4 LIM homeobox 3 Nucleic acid binding 1.1E-02 0.644 0.462
LHX4 Q969G2 LIM homeobox 4 Nucleic acid binding 1.8E-02 0.621 0.462
MAGEL2 Q9UJ55 MAGE family member L2 Cell adhesion 0.98 0.560 0.654
NFKB2 Q00653 nuclear factor kappa B subunit 2 Transcription factor 1.00 0.509 0.808
OTX2 P32243 orthodenticle homeobox 2 Transcription factor 0.92 0.514 0.808
PAX6 P26367 paired box 6 1.00 0.450 0.769
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885