Disease: Mild Mental Retardation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
C12orf57 Q99622 chromosome 12 open reading frame 57 5.2E-05 0.641 0.500
CA8 P35219 carbonic anhydrase 8 8.3E-03 0.595 0.654
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
CDKL5 O76039 cyclin dependent kinase like 5 Kinase 1.00 0.522 0.692
DCC P43146 DCC netrin 1 receptor 0.99 0.471 0.808
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
EZR P15311 ezrin Cellular structure 0.18 0.476 0.808
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
FRAXE fragile site, folic acid type, rare, fra(X)(q28) E 0.636 0.462
LINS1 Q8NG48 lines homolog 1 2.4E-07 0.691 0.231
MAN1B1 Q9UKM7 mannosidase alpha class 1B member 1 Chaperone 1.2E-08 0.606 0.577
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
METTL23 Q86XA0 methyltransferase like 23 1.3E-07 0.682 0.231
NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit Enzyme 1.00 0.700 0.423
NDST1 P52848 N-deacetylase and N-sulfotransferase 1 1.00 0.608 0.692
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
PHIP Q8WWQ0 pleckstrin homology domain interacting protein Epigenetic regulator 1.00 0.595 0.769
POLR3B Q9NW08 RNA polymerase III subunit B Enzyme 1.7E-23 0.628 0.654
PRRT2 Q7Z6L0 proline rich transmembrane protein 2 0.58 0.448 0.808
PTCH1 Q13635 patched 1 1.00 0.398 0.885