Disease: Sezary Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CCR4 P51679 C-C motif chemokine receptor 4 G-protein coupled receptor 6.9E-02 0.510 0.731
CD28 P10747 CD28 molecule 0.36 0.436 0.885
CXCL13 O43927 C-X-C motif chemokine ligand 13 Signaling 0.83 0.472 0.731
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
HLA-G P17693 major histocompatibility complex, class I, G 1.4E-11 0.461 0.769
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL21 Q9HBE4 interleukin 21 0.63 0.441 0.769
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL5 P05113 interleukin 5 5.7E-03 0.437 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PLCG1 P19174 phospholipase C gamma 1 Enzyme 7.9E-05 0.564 0.692
RAG2 P55895 recombination activating 2 2.0E-02 0.507 0.769
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
TBX21 Q9UL17 T-box transcription factor 21 Transcription factor 1.00 0.541 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962