Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PRSS1 | P07477 | serine protease 1 | Enzyme | 4.1E-11 | 0.563 | 0.692 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
KL | Q9UEF7 | klotho | Enzyme | 2.2E-04 | 0.448 | 0.769 |
SERPINA1 | P01009 | serpin family A member 1 | Enzyme modulator | 6.8E-08 | 0.410 | 0.923 |
RALBP1 | Q15311 | ralA binding protein 1 | Enzyme modulator | 0.15 | 0.536 | 0.654 |
RCBTB1 | Q8NDN9 | RCC1 and BTB domain containing protein 1 | Enzyme modulator | 1.6E-06 | 0.572 | 0.692 |
EHMT1 | Q9H9B1 | euchromatic histone lysine methyltransferase 1 | Epigenetic regulator | 1.00 | 0.460 | 0.808 |
CASR | P41180 | calcium sensing receptor | G-protein coupled receptor | 4.7E-02 | 0.410 | 0.846 |
GLP1R | P43220 | glucagon like peptide 1 receptor | G-protein coupled receptor | 0.29 | 0.471 | 0.846 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
EPHB1 | P54762 | EPH receptor B1 | Kinase | 1.00 | 0.518 | 0.846 |
EPHB2 | P29323 | EPH receptor B2 | Kinase | 1.00 | 0.374 | 0.846 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
MAPK8 | P45983 | mitogen-activated protein kinase 8 | Kinase | 1.00 | 0.397 | 0.885 |
RIPK1 | Q13546 | receptor interacting serine/threonine kinase 1 | Kinase | 7.9E-03 | 0.479 | 0.769 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
VDR | P11473 | vitamin D receptor | Nuclear receptor | 1.7E-05 | 0.352 | 0.885 |
EGR1 | P18146 | early growth response 1 | Nucleic acid binding | 0.35 | 0.433 | 0.923 |
KHDRBS1 | Q07666 | KH RNA binding domain containing, signal transduction associated 1 | Nucleic acid binding | 0.99 | 0.457 | 0.846 |
LILRB1 | Q8NHL6 | leukocyte immunoglobulin like receptor B1 | Receptor | 5.7E-14 | 0.510 | 0.769 |
ANGPT2 | O15123 | angiopoietin 2 | Signaling | 0.83 | 0.410 | 0.846 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |