Disease: Congenital Hyperinsulinism
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CDKN2C P42773 cyclin dependent kinase inhibitor 2C 0.40 0.527 0.654
CMA1 P23946 chymase 1 Enzyme 7.6E-09 0.514 0.692
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
GCG P01275 glucagon 3.5E-02 0.431 0.885
GCK P35557 glucokinase Kinase 0.63 0.523 0.808
GLP1R P43220 glucagon like peptide 1 receptor G-protein coupled receptor 0.29 0.471 0.846
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808
INS P01308 insulin 0.30 0.445 0.923
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
LEP P41159 leptin 0.46 0.349 0.846
MCAT Q8IVS2 malonyl-CoA-acyl carrier protein transacylase 3.1E-04 0.524 0.808
MCTS1 Q9ULC4 MCTS1 re-initiation and release factor Receptor 0.87 0.552 0.692
MEN1 O00255 menin 1 1.00 0.444 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
PAX4 O43316 paired box 4 4.2E-04 0.644 0.423
PDHX O00330 pyruvate dehydrogenase complex component X Enzyme 9.7E-05 0.595 0.692
PDX1 P52945 pancreatic and duodenal homeobox 1 1.8E-02 0.530 0.654
RIT2 Q99578 Ras like without CAAX 2 Enzyme modulator 6.3E-04 0.647 0.538