Disease: Crohn's disease of large bowel
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SLC11A1 P49279 solute carrier family 11 member 1 Transporter 1.5E-19 0.525 0.846
NKX2-3 Q8TAU0 NK2 homeobox 3 Transcription factor 0.95 0.716 0.231
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
FGF19 O95750 fibroblast growth factor 19 Signaling 0.57 0.548 0.615
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
GUCY2C P25092 guanylate cyclase 2C Kinase 1.4E-30 0.599 0.577
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
CCR9 P51686 C-C motif chemokine receptor 9 G-protein coupled receptor 4.2E-03 0.573 0.692
GPBAR1 Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 1.4E-09 0.548 0.731
MST1 P26927 macrophage stimulating 1 Enzyme 4.8E-19 0.465 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
ACAD8 Q9UKU7 acyl-CoA dehydrogenase family member 8 Enzyme 5.6E-14 0.506 0.885
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NFKBIA P25963 NFKB inhibitor alpha 0.99 0.487 0.885
PTPN2 P17706 protein tyrosine phosphatase non-receptor type 2 1.00 0.538 0.692