Disease: Actinic keratosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FAP Q12884 fibroblast activation protein alpha Enzyme 1.9E-28 0.496 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
H3P10 H3 histone pseudogene 10 0.350 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRT17 Q04695 keratin 17 1.1E-11 0.531 0.654
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PI3 P19957 peptidase inhibitor 3 Enzyme modulator 0.17 0.570 0.692
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808