Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
FLCN | Q8NFG4 | folliculin | 0.79 | 0.537 | 0.885 | |
WRN | Q14191 | WRN RecQ like helicase | Enzyme | 2.6E-34 | 0.524 | 0.808 |
STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |
KLLN | B2CW77 | killin, p53 regulated DNA replication inhibitor | 5.1E-03 | 0.578 | 0.654 | |
BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 |