Disease: Autosomal Recessive Polycystic Kidney Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885
AVPR2 P30518 arginine vasopressin receptor 2 G-protein coupled receptor 0.56 0.568 0.769
BICC1 Q9H694 BicC family RNA binding protein 1 Transporter 0.84 0.636 0.577
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CDC25A P30304 cell division cycle 25A Enzyme 0.84 0.564 0.615
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
DZIP1L Q8IYY4 DAZ interacting zinc finger protein 1 like Nucleic acid binding 2.4E-25 0.769 0.308
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692
HNF1B P35680 HNF1 homeobox B Nucleic acid binding 1.00 0.473 0.808
IFT88 Q13099 intraflagellar transport 88 7.1E-11 0.621 0.654
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NEK1 Q96PY6 NIMA related kinase 1 Kinase 1.9E-25 0.575 0.769
NEK8 Q86SG6 NIMA related kinase 8 Kinase 6.5E-09 0.631 0.500
NPHP3 Q7Z494 nephrocystin 3 9.8E-16 0.597 0.654
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PKD1 P98161 polycystin 1, transient receptor potential channel interacting 1.00 0.493 0.769
PKD2 Q13563 polycystin 2, transient receptor potential cation channel Ion channel 1.7E-04 0.552 0.731
PKD2L1 Q9P0L9 polycystin 2 like 1, transient receptor potential cation channel Ion channel 1.6E-27 0.565 0.731
PKHD1 P08F94 PKHD1 ciliary IPT domain containing fibrocystin/polyductin 1.2E-47 0.576 0.654
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846