Disease: Flexion contracture of proximal interphalangeal joint
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
L1CAM P32004 L1 cell adhesion molecule 1.00 0.475 0.769
MAP3K7 O43318 mitogen-activated protein kinase kinase kinase 7 Kinase 1.00 0.477 0.808
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769
TPM2 P07951 tropomyosin 2 Cellular structure 2.4E-04 0.530 0.654
NAA10 P41227 N-alpha-acetyltransferase 10, NatA catalytic subunit Enzyme 0.76 0.535 0.692