Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
WNK1 | Q9H4A3 | WNK lysine deficient protein kinase 1 | Kinase | 1.00 | 0.416 | 0.846 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
DICER1 | Q9UPY3 | dicer 1, ribonuclease III | Enzyme | 1.00 | 0.446 | 0.846 |
ARID1B | Q8NFD5 | AT-rich interaction domain 1B | 1.00 | 0.503 | 0.846 | |
SOS1 | Q07889 | SOS Ras/Rac guanine nucleotide exchange factor 1 | Enzyme modulator | 1.00 | 0.485 | 0.808 |
HDAC4 | P56524 | histone deacetylase 4 | Epigenetic regulator | 1.00 | 0.484 | 0.885 |
LRP1 | Q07954 | LDL receptor related protein 1 | 1.00 | 0.482 | 0.769 | |
NSD1 | Q96L73 | nuclear receptor binding SET domain protein 1 | Epigenetic regulator | 1.00 | 0.505 | 0.769 |
RREB1 | Q92766 | ras responsive element binding protein 1 | 1.00 | 0.500 | 0.808 | |
PKD1 | P98161 | polycystin 1, transient receptor potential channel interacting | 1.00 | 0.493 | 0.769 | |
SF3B1 | O75533 | splicing factor 3b subunit 1 | Nucleic acid binding | 1.00 | 0.511 | 0.731 |
MYH9 | P35579 | myosin heavy chain 9 | 1.00 | 0.505 | 0.808 |