Source: CLINVAR ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SF3B2 Q13435 splicing factor 3b subunit 2 1.00 0.780 0.308
TGM6 O95932 transglutaminase 6 1.1E-24 0.644 0.423
DDX41 Q9UJV9 DEAD-box helicase 41 5.6E-08 0.636 0.538
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
CSF3R Q99062 colony stimulating factor 3 receptor Signaling 1.5E-10 0.550 0.692
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692
CEBPA P49715 CCAAT enhancer binding protein alpha Transcription factor 0.55 0.496 0.692
DNAJC21 Q5F1R6 DnaJ heat shock protein family (Hsp40) member C21 2.1E-07 0.606 0.731
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
JAK1 P23458 Janus kinase 1 Kinase 1.00 0.474 0.769
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923