Disease: Achondroplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FGF1 P05230 fibroblast growth factor 1 Signaling 0.44 0.507 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
GRB10 Q13322 growth factor receptor bound protein 10 Receptor 0.94 0.628 0.615
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL36RN Q9UBH0 interleukin 36 receptor antagonist 3.4E-08 0.638 0.538
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MSX1 P28360 msh homeobox 1 Transcription factor 0.17 0.525 0.731
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808