Disease: Acromegaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GHR P10912 growth hormone receptor Signaling 8.4E-05 0.490 0.846
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
H3P10 H3 histone pseudogene 10 0.350 0.846
IGFBP3 P17936 insulin like growth factor binding protein 3 Enzyme modulator 0.91 0.439 0.808
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TP73 O15350 tumor protein p73 Transcription factor 1.00 0.449 0.808
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923