Disease: Mastocytosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
FIP1L1 Q6UN15 factor interacting with PAPOLA and CPSF1 0.79 0.575 0.577
IKZF1 Q13422 IKAROS family zinc finger 1 Transcription factor 1.00 0.533 0.769
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SERPINB6 P35237 serpin family B member 6 Enzyme modulator 1.1E-04 0.547 0.769
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808