Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
RHOA P61586 ras homolog family member A Enzyme modulator 0.60 0.502 0.808
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923
TNFAIP3 P21580 TNF alpha induced protein 3 Enzyme 1.00 0.481 0.808
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692
IKZF1 Q13422 IKAROS family zinc finger 1 Transcription factor 1.00 0.533 0.769