Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
ELN P15502 elastin 2.1E-14 0.415 0.885
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
NKX2-1 P43699 NK2 homeobox 1 Transcription factor 0.36 0.457 0.808
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846
GPC3 P51654 glypican 3 1.00 0.466 0.808
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769