Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
MSLN | Q13421 | mesothelin | Extracellular structure | 5.9E-25 | 0.525 | 0.692 |
SELENBP1 | Q13228 | selenium binding protein 1 | Immune response | 3.2E-16 | 0.493 | 0.846 |
ITGA8 | P53708 | integrin subunit alpha 8 | 6.1E-13 | 0.641 | 0.577 | |
ATR | Q13535 | ATR serine/threonine kinase | Kinase | 3.5E-09 | 0.456 | 0.923 |
KLK10 | O43240 | kallikrein related peptidase 10 | Enzyme | 4.4E-07 | 0.608 | 0.538 |
ALOX5 | P09917 | arachidonate 5-lipoxygenase | Enzyme | 1.2E-06 | 0.447 | 0.885 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
CAV1 | Q03135 | caveolin 1 | Enzyme modulator | 8.3E-03 | 0.388 | 0.885 |
MAPK3 | P27361 | mitogen-activated protein kinase 3 | Kinase | 3.7E-02 | 0.379 | 0.885 |
GADD45A | P24522 | growth arrest and DNA damage inducible alpha | 4.4E-02 | 0.526 | 0.769 | |
BIRC5 | O15392 | baculoviral IAP repeat containing 5 | Enzyme modulator | 5.6E-02 | 0.495 | 0.731 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
SOD2 | P04179 | superoxide dismutase 2 | Enzyme | 0.15 | 0.379 | 0.923 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
AREG | P15514 | amphiregulin | Signaling | 0.35 | 0.487 | 0.769 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
TYMS | P04818 | thymidylate synthetase | Enzyme | 0.72 | 0.425 | 0.846 |
RNF43 | Q68DV7 | ring finger protein 43 | 0.73 | 0.584 | 0.577 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |