Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
SPP1 | P10451 | secreted phosphoprotein 1 | 2.1E-06 | 0.353 | 0.885 | |
NFE2L2 | Q16236 | nuclear factor, erythroid 2 like 2 | Enzyme | 3.6E-03 | 0.357 | 0.885 |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
FN1 | P02751 | fibronectin 1 | Signaling | 1.4E-03 | 0.365 | 0.962 |