Disease: ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALCAM Q13740 activated leukocyte cell adhesion molecule Cell adhesion 0.73 0.502 0.808
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDH1 P12830 cadherin 1 0.15 0.401 0.808
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
S100A6 P06703 S100 calcium binding protein A6 Calcium-binding protein 0.18 0.510 0.808
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962