Disease: Dissection of aorta
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
ELN P15502 elastin 2.1E-14 0.415 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
LOX P28300 lysyl oxidase 0.99 0.447 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
MMP12 P39900 matrix metallopeptidase 12 Enzyme 0.484 0.885
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846