Disease: Focal glomerulosclerosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SLC12A3 P55017 solute carrier family 12 member 3 Transporter 3.0E-32 0.493 0.808
MMRN1 Q13201 multimerin 1 2.1E-25 0.465 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
TAGLN Q01995 transgelin Cellular structure 8.5E-02 0.540 0.692
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846