| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
| CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
| CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
| EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
| FBXW7 | Q969H0 | F-box and WD repeat domain containing 7 | Enzyme modulator | 1.00 | 0.465 | 0.808 |
| FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
| IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
| MYCN | P04198 | MYCN proto-oncogene, bHLH transcription factor | Transcription factor | 0.89 | 0.454 | 0.808 |
| MYCNOS | P40205 | MYCN opposite strand | 0.700 | 0.462 | ||
| NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
| PTCH2 | Q9Y6C5 | patched 2 | 3.4E-16 | 0.563 | 0.692 | |
| SF3B2 | Q13435 | splicing factor 3b subunit 2 | 1.00 | 0.780 | 0.308 | |
| SMO | Q99835 | smoothened, frizzled class receptor | G-protein coupled receptor | 4.3E-07 | 0.489 | 0.731 |
| SUFU | Q9UMX1 | SUFU negative regulator of hedgehog signaling | 1.00 | 0.493 | 0.769 | |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
| WRN | Q14191 | WRN RecQ like helicase | Enzyme | 2.6E-34 | 0.524 | 0.808 |