Disease: Refractory anaemia with excess blasts
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CHEK1 O14757 checkpoint kinase 1 Kinase 3.1E-08 0.492 0.808
CIP2A Q8TCG1 cellular inhibitor of PP2A 1.4E-13 0.524 0.808
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
DLK1 P80370 delta like non-canonical Notch ligand 1 Signaling 3.5E-02 0.527 0.692
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
ITGA2B P08514 integrin subunit alpha 2b 1.5E-16 0.493 0.692
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MCL1 Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 0.96 0.430 0.808
MIR29B1 microRNA 29b-1 0.485 0.846
MIR29B2 microRNA 29b-2 0.484 0.885
MOGS Q13724 mannosyl-oligosaccharide glucosidase 5.8E-11 0.626 0.731
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731