Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACD Q96AP0 ACD shelterin complex subunit and telomerase recruitment factor 1.1E-12 0.603 0.731
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
DDB2 Q92466 damage specific DNA binding protein 2 Nucleic acid binding 7.4E-06 0.576 0.654
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
GNA11 P29992 G protein subunit alpha 11 Enzyme modulator 0.89 0.563 0.731
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
MAP2K2 P36507 mitogen-activated protein kinase kinase 2 Kinase 0.97 0.534 0.731
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808
POLH Q9Y253 DNA polymerase eta 3.5E-09 0.663 0.462
POT1 Q9NUX5 protection of telomeres 1 Nucleic acid binding 0.85 0.560 0.731
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
TERF2IP Q9NYB0 TERF2 interacting protein 2.7E-05 0.548 0.731