| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
| CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
| CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
| HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| MAP2K2 | P36507 | mitogen-activated protein kinase kinase 2 | Kinase | 0.97 | 0.534 | 0.731 |
| PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
| PALLD | Q8WX93 | palladin, cytoskeletal associated protein | 5.3E-06 | 0.628 | 0.615 | |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| RNF43 | Q68DV7 | ring finger protein 43 | 0.73 | 0.584 | 0.577 | |
| SDHB | P21912 | succinate dehydrogenase complex iron sulfur subunit B | Enzyme | 2.4E-04 | 0.474 | 0.846 |
| SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
| STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |