Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CLDN5 O00501 claudin 5 Cell-cell junction 0.90 0.559 0.769
CLDN2 P57739 claudin 2 Cell-cell junction 0.70 0.575 0.692
VILL O15195 villin like Cellular structure 3.9E-23
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
ACSL5 Q9ULC5 acyl-CoA synthetase long chain family member 5 Enzyme 2.9E-09 0.641 0.500
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
SLPI P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 9.0E-04 0.449 0.846
MUC2 Q02817 mucin 2, oligomeric mucus/gel-forming Enzyme modulator 9.4E-10 0.486 0.808
SMARCA2 P51531 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Epigenetic regulator 1.00 0.527 0.769
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
CLCA1 A8K7I4 chloride channel accessory 1 Ion channel 3.3E-09 0.659 0.538
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
GUCY2C P25092 guanylate cyclase 2C Kinase 1.4E-30 0.599 0.577
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
FASLG P48023 Fas ligand Signaling 0.18 0.430 0.885
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808