Disease: Nystagmus, CTCAE 5.0
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CRYAA A0A140G945 P02489 crystallin alpha A 0.17 0.653 0.385
PLK4 O00444 polo like kinase 4 Kinase 7.1E-06 0.551 0.731
PEX7 O00628 peroxisomal biogenesis factor 7 8.2E-13 0.603 0.615
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
PHYH O14832 phytanoyl-CoA 2-hydroxylase 2.4E-06 0.659 0.577
SEMA3E O15041 semaphorin 3E Signaling 8.7E-09 0.515 0.769
CEP290 O15078 centrosomal protein 290 1.1E-60 0.517 0.769
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
PHGDH O43175 phosphoglycerate dehydrogenase Enzyme 1.3E-04 0.484 0.885
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
PDE6D O43924 phosphodiesterase 6D Enzyme 6.4E-03 0.623 0.577
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808
LRP4 O75096 LDL receptor related protein 4 1.4E-06 0.568 0.692
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846
BEST1 O76090 bestrophin 1 Ion channel 1.8E-12 0.465 0.885
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
PIGN O95427 phosphatidylinositol glycan anchor biosynthesis class N Extracellular structure 2.3E-21 0.558 0.615
SIX6 O95475 SIX homeobox 6 Transcription factor 0.52 0.588 0.654
WDPCP O95876 WD repeat containing planar cell polarity effector 1.1E-10 0.576 0.769
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923