Disease: Byzanthine arch palate
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
LMNA P02545 lamin A/C 1.00 0.384 0.885
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FLNA P21333 filamin A 1.00 0.419 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
SMS P52788 spermine synthase 0.97 0.491 0.846
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808